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These results, combined with orforgliprons once-daily oral dosing and broad scalability, reinforce its potential as a foundational treatment for type 2 diabetes. Eli Lilly also recently presented detailed results from the ATTAIN-1 trial, which investigated orforglipron in adults with obesity or overweight without diabetes, at the European Association for the Study of Diabetes (EASD) Annual Meeting 2025

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Following DAPI counterstaining (Solarbio, China), samples were imaged using an inverted fluorescence microscope (Zeiss, Germany)

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doi: 10.1371/journal.pone.0100519 70

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